Hydrotropic polymer-based paclitaxel-loaded self-assembled nanoparticles: preparation and biological evaluation
نویسندگان
چکیده
منابع مشابه
Preparation and evaluation of paclitaxel-loaded PEGylated immunoliposome.
A sterically stabilized paclitaxel-loaded liposome tailored to target human breast cancer cells was developed, thereby promoting the efficiency of intracellular delivery of paclitaxel through receptor-mediated endocytosis. Results indicated that the targeting moiety (thiolated Herceptin) was successfully coupled to the distal reactive maleimide terminus of the poly (ethylene glycol)-phospholipi...
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متن کاملPREPARATION AND OPTIMISATIONOF PALM-BASED LIPID NANOPARTICLES LOADED WITH GRISEOFULVIN
Palm-based lipid nanoparticle formulation loaded with griseofulvin was prepared by hot homogenisation and a solvent-free method. The optimum griseofulvin loaded lipid nanoparticles were prepared via stages of optimisation, such as high pressure homogenisation (HPH) parameters, lipid and surfactant screening and selection of suitable lipid to surfactant ratios; followed by photon correlation stu...
متن کاملHydrotropic polymer micelle system for delivery of paclitaxel.
Hydrotropic polymer micelle system has been developed for delivery of poorly water-soluble drugs such as paclitaxel. Hydrotropic polymers based on N,N-diethylnicotinamide were synthesized and used as a hydrophobic block for constructing amphiphilic block copolymers. The hydrotropic block copolymers self-assembled to form micelles in aqueous media. The size of the prepared polymer micelles was i...
متن کاملPREPARATION AND OPTIMISATIONOF PALM-BASED LIPID NANOPARTICLES LOADED WITH GRISEOFULVIN
Palm-based lipid nanoparticle formulation loaded with griseofulvin was prepared by hot homogenisation and a solvent-free method. The optimum griseofulvin loaded lipid nanoparticles were prepared via stages of optimisation, such as high pressure homogenisation (HPH) parameters, lipid and surfactant screening and selection of suitable lipid to surfactant ratios; followed by photon correlation stu...
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ژورنال
عنوان ژورنال: RSC Advances
سال: 2017
ISSN: 2046-2069
DOI: 10.1039/c7ra04563h